Dr. Sangram Bagh, FRSC

Recent Journal Publications 1. Deepro Bonnerjee, Saswata Chakraborty,  Biyas Mukherjee, Ritwika Basu, Abhishek Paul, and Sangram Bagh* (2024) Multicellular artificial neural network-type architectures demonstrate computational problem solving. Nature Chemical Biology (2024). https://doi.org/10.1038/s41589-024-01711-4 (This work has been featured in New Scientist (https://www.newscientist.com/article/2448167-bacteria-can-work-as-a-team-to-spot-prime-numbers-and-vowels) ,  Physics World (https://physicsworld.com/a/genetically-engineered-bacteria-solve-computational-problems), and in many National and International media in various languages) 2. Rajkamal Srivastava and Sangram Bagh* (2023) , A Logically Reversible Double Feynman Gate with Molecular Engineered Bacteria Arranged in an Artificial Neural Network-Type Architecture, ACS Synthetic Biology, 2023, 12, 1, 51–60 (Front Cover Page Article)   (This work is featured as news in Communications of the ACM, https://cacm.acm.org/news/fungal-architectures-and-logical-bacteria/) 3. Rajkamal Srivastava, Kathakali Sarkar, Deepro Bonnerjee, and Sangram Bagh* (2022) Synthetic Genetic Reversible Feynman Gate in a Single E. coli Cell and Its Application in Bacterial to Mammalian Cell Information Transfer, ACS Synthetic Biology, https://doi.org/10.1021/acssynbio.1c00392    This work is highlighted in Nature India (https://www.nature.com/articles/d44151-022-00032-6)   4. Kathakali Sarka,   Deepro Bonnerjee,   Rajkamal Srivastava  and  Sangram Bagh *  (2021) A single layer artificial neural network type architecture with molecular engineered bacteria for reversible and irreversible computing, Chem. Sci., 2021,12, 15821-15832 (Front Cover Page Article) AND This work is featured in Nature India  (https://www.nature.com/articles/d44151-021-00081-3)   5. Kathakali Sarkar, Saswata Chakrabarty, Deepro Bonnerjee, Sangram Bagh* (2021), Distributed Computing with Engineered Bacteria and Its Application in Solving Chemically Generated 2 × 2 Maze Problems, ACS Synthetic Biology, 10 (10), 2456-2464 (This work is featured in MIT Technology Review,  (https://www.technologyreview.com/2021/11/09/1039107/e-coli-maze-solving-biocomputer/) and in multiple international science/technology news media 6. Sayak Mukhopadhyay, and Sangram Bagh* (2020). “A Microgravity Responsive Synthetic Genetic Device in Escherichia Coli.”  Biosensors and Bioelectronics, vol. 167, Nov. 2020, p. 112462. , IF: 10.257 7.  Mukhopadhyay, S, Sarkar, K, Srivastava, R, Pal, A, Bagh, S. (2020) Processing two environmental chemical signals with a synthetic genetic IMPLY gate, a 2‐input‐2‐output integrated logic circuit, and a process pipeline to optimize its systems chemistry in Escherichia coli. Biotechnology and Bioengineering. 2020; 1– 11. https://doi.org/10.1002/bit.2  8. Deepro Bonnerjee, Sayak Mukhopadhyay and Sangram Bagh* (2019) Design, Fabrication, and Device Chemistry of a 3-Input-3-Output Synthetic Genetic Combinatorial Logic Circuit with a 3-Input AND Gate in a Single Bacterial Cell, Bioconjugate Chemistry,  30, 12, 3013-30207  (Front cover page article)  9. Kathakali Sarkar, Sayak Mukhopadhyay, Deepro Bonnerjee, Rajkamal Srivastava and Sangram Bagh*(2019) A frame-shifted gene, which rescued its function by non-natural start codons and its application in constructing synthetic gene circuits. Journal of Biological Engineering, 2019 13:20 10. P Majumder, K Roy, S Bagh, D Mukhopadhyay (2019) Receptor tyrosine kinases (RTKs) consociate in regulatory clusters in Alzheimer’s disease and type 2 diabetes Molecular and cellular biochemistry, 1-12 doi: 10.1007/s11010-019-03560-5 11. Raktim Roy, Phani P Shilpaand Sangram Bagh* (2016) A Systems Biology Analysis Unfolds the Molecular Pathways and Networks of Two Proteobacteria in Spaceflight and Simulated Microgravity Conditions, Astrobiology, 16, 677–689 * corresponding author  (This work is highlighted as a high impact article by the editorial board of the Astrobiology)    12. Shounal Baksi , Sangram Bagh, Sandip Sarkar  and Debashis Mukhopadhyay D (2016) Systemic study of a natural feedback loop in Huntington's disease at the onset of neurodegeneration.  Biosystems 150, 46-51 13.  Sayak Mukhopadhyay, Rohini Saha, Anbarasi Palanisamy, Madhurima Ghosh, Anupriya Biswas,Saheli Roy, Arijit Pal, Kathakali Sarkar and Sangram Bagh* (2016) A systems biology pipeline identifies new immune and disease related molecular signatures and networks in human cells during microgravity exposure, Scientific Reports, 6:25975, DOI: .1038/srep25975, IF: 4.249.  (This work is highlighted in Nature India, May 2016 and Times of India) 14.  Sangram Bagh, (2016) Reprogramming living cells with an engineering language, Physics News, 46, 43-52 (Invited review article)    Book Chapters 1.  Kathakali Sarkar and Sangram Bagh (2022), Synthetic Gene Circuits for Higher Order Information Processing, in New Frontiers and Applications of Synthetic Biology, Edited by : V. Singh, Academic Press. Elsevier. 372-92 2.      Deepro Bonnerjee and Sangram Bagh (2021), Application of CRISPR-Cas systems in neuroscience, Advances in CRISPR/Cas and Related Technologies, Edited by: D. Ghosh, Academic Press. Elsevier. 231-64