Dr. Kaushik Sengupta

Sengupta D, Sengupta K. Lamin A K97E leads to NF-κB-mediated dysfunction of inflammatory responses in Dilated Cardiomyopathy. Biology of the Cell. 2024;116(3). Sengupta KS Duhita, Mukhopadhyay A. Elevated Levels of Lamin A Promote HR and NHEJ-Mediated Repair Mechanisms in High-Grade Ovarian Serous Carcinoma Cell Line. Cells. 2023;12(5):757-783. Mukherjee KS Chandrayee, Sengupta Duhita, Maganti L, Mahendar M, et al. Slower diffusion and anomalous association of R453W lamin A protein alter nuclear architecture in AD-EDMD. RSC Advances. 2022;12(49):32129-32141. Sengupta D, Sengupta K. Elevated levels of lamin A promote HR and NHEJ-mediated repair mechanisms in etoposide-treated ovarian cancer cells. bioRxiv. 2022.09.02.506330. Sengupta D, Sengupta K. Lamin A and telomere maintenance in aging: Two to Tango. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 2022;825. Sengupta D, Ali SN, Bhattacharya A, Mustafi J, Mukhopadhyay A, et al. A deep hybrid learning pipeline for accurate diagnosis of ovarian cancer based on nuclear morphology. PLoS One. 2022;17(1):e0261181. Mukherjee C, Bera M, Koti Ainavarapu SR, Sengupta K. Pulling the springs of a cell by single-molecule force spectroscopy. Emerging Topics in Life Sciences. 2021;5(1):77-87. Sengupta D, Ali SN, Bhattacharya A, Mustafi J, Mukhopadhyay A, et al. Nuclear Morphology Optimized Deep Hybrid Learning (NUMODRIL) for Accurate Diagnosis and Prognosis of Ovarian Cancer. 2021. Mukherjee C, Kundu A, Dey R, Banerjee A, Sengupta K. Active microrheology using pulsed optical tweezers to probe viscoelasticity of lamin A. Soft Matter. 2021;17(28):6787-6796. Sengupta D, Mukhopadhyay A, Sengupta K. Emerging roles of lamins and DNA damage repair mechanisms in ovarian cancer. Biochemical Society Transactions. 2020;48(5):2317-2333. Banerjee A, Sengupta K. Alteration of epigenetic landscape by lamin A mutations: Hallmark of Dilated Cardiomyopathy. bioRxiv. 2020.05.01.071803. Bera M, Sengupta K. Nuclear filaments: role in chromosomal positioning and gene expression. Nucleus. 2020;11(1):99-110. Bera M, Kumar R, Sinha B, Sengupta K. Nuclear deformation and anchorage defect induced by DCM mutants in lamin A. bioRxiv. 2019;611665. Dutta S, Das JK, Maganti L, Bhattacharyya M, Bhattacharyya D, et al. Skeletal Muscle Dystrophy mutant of lamin A alters the structure and dynamics of the Ig fold domain. Scientific Reports. 2018;8(1):13793. Dutta S, Bhattacharyya M, Sengupta K. Changes in the nuclear envelope in Laminopathies. Biochemical and Biophysical Roles of Cell Surface Molecules. 2018:31-38. Bhattacharjee P, Dasgupta D, Sengupta K. DCM associated LMNA mutations cause distortions in lamina structure and assembly. Biochimica et Biophysica Acta (BBA) - General Subjects. 2017;1861(11):2598-2608. Dey SK, Singh RK, Chattoraj S, Saha S, Das A, Bhattacharyya K, et al. Differential role of nonmuscle myosin II isoforms during blebbing of MCF-7 cells. Molecular Biology of the Cell. 2017;28(8):1034-1042. Dutta S, Bhattacharyya M, Sengupta K. Implications and assessment of the elastic behavior of lamins in laminopathies. Cells. 2016;5(4):37. Bera M, Ainavarapu SRK, Sengupta K. Significance of 1B and 2B domains in modulating elastic properties of lamin A. Scientific Reports. 2016;6(1):27879. Bhattacharjee P, Dasgupta D, Sengupta K. Molecular events in lamin B1 homopolymerization: A biophysical characterization. The Journal of Physical Chemistry B. 2015;119(44):14014-14021. Banerjee A, Ghoshal PK, Sengupta K. Novel linkage of LMNA single nucleotide polymorphism with dilated cardiomyopathy in an Indian case study. IJC Heart & Vasculature. 2015;7:99-105. Roy J, Mitra S, Sengupta K, Mandal AK. Hsp70 clears misfolded kinases that partitioned into distinct quality-control compartments. Molecular Biology of the Cell. 2015;26(9):1583-1600. Bera M, Kotamarthi HC, Dutta S, Ray A, Ghosh S, Bhattacharyya D, et al. Characterization of unfolding mechanism of human lamin A Ig fold by single-molecule force spectroscopy: Implications in EDMD. Biochemistry. 2014;53(46):7247-7258. Banerjee A, Rathee V, Krishnaswamy R, Bhattacharjee P, Ray P, et al. Viscoelastic behavior of human lamin A proteins in the context of dilated cardiomyopathy. PLoS One. 2013;8(12):e83410. Bhattacharjee P, Banerjee A, Banerjee A, Dasgupta D, Sengupta K. Structural alterations of Lamin A protein in dilated cardiomyopathy. Biochemistry. 2013;52(24):4229-4241.