Basepairs involving Hoogsteen edge of Guanine and Hoogsteen edge of Cytosine

Basepairs involving Hoogsteen(H) edge of Guanine and Hoogsteen(H) edge of Cytosine is shown. Highlighted examples are found from RNA crystal structures obtained from PDB.

Base pairs stabilized by C-H...N/O interactions along with N-H...N/O hydrogen bonds

Basepair (type & Orientation)	*Frequency	Example	Hydrogen bonding atoms with their precursors
G:C h:h Cis	0	Optimized Model Structure	N1-O6...N4-N3 N9-N7...C5-C2
G:C h:h Trans	12/ 2	Residue Nos. 9(C)-23(C) PDB ID 2DER	N9-N7...N4-N3 N1-O6...C5-N1

Basepair

(type & Orientation)

*Frequency

Example

Hydrogen bonding atoms with their precursors

G:C h:h Cis

Optimized Model Structure

N1-O6...N4-N3

N9-N7...C5-C2

G:C h:h Trans

12/
2

Residue Nos. 9(C)-23(C) PDB ID 2DER

N9-N7...N4-N3

N1-O6...C5-N1