Basepairs involving WatsonCrick edge of Cytosine and Hoogsteen edge of Cytosine

Basepairs involving WatsonCrick(W) edge of Cytosine and Hoogsteen(H) edge of Cytosine is shown. Highlighted examples are found from RNA crystal structures obtained from PDB.

Base pairs stabilized by C-H...N/O interactions along with N-H...N/O hydrogen bonds

Basepair (type & Orientation)	*Frequency	Example	Hydrogen bonding atoms with their precursors
C:C w:h Cis	5	Optimized Model Structure	C6-N3...N4-N3 N1-O2...C5-C2
C:C w:h Trans	8/ 1	Optimized Model Structure	N1-O2...N4-N3 C6-N3...C5-C2

Basepair

(type & Orientation)

*Frequency

Example

Hydrogen bonding atoms with their precursors

C:C w:h Cis

Optimized Model Structure

C6-N3...N4-N3

N1-O2...C5-C2

C:C w:h Trans

8/
1

Optimized Model Structure

N1-O2...N4-N3

C6-N3...C5-C2